The only coin I’m aware of that has any hope of legitimately obtaining a 1000x jump in dollar value would be Namecoin. NMC is the only well known and massively supported coin with a market cap low enough to possibly achieve a 1000x return. I think if more people were aware of its hashrate and active development as well as a familiarity with the problem that Namecoin solves, its value would explode in response. A lot of folks think it is a dead chain and I think regulators likely have some responsibility for why it isn’t listed on more exchanges. Otherwise I believe the price would be much higher.