Actually, for now, another pretty good thing for Napoli is that Kvaratskhelia and Osimhen, who are in good condition, are not there because obviously this can make at least the risk of fatigue and injury minimized for them and of course this is an advantage too, although there are indeed some opportunities for them leave but this is still just a rumour.
But on the other hand, of course, there will be some additional flying hours if players take part in the world cup.
In general, not so many Napoli players are in the world cup, so the potential for Napoli to continue to win in the second half of the season is clearly very wide open because Napoli can still formulate their best strategy to win games in the second half of the season. And also Napoli can improve their performances in the Champions League because the Napoli coach knows how the condition of their players is at the moment and also sees the opposing team's consistency starting to decline.
In this world cup, only 5 players from Napoli left and that was Kim Min Jae (South Korea), Mathias Oliviera (Uruguay), Frank Anguissa (Cameroon), Piotr Zielinski (Poland) and Hirving Lozano (Mexico). and actually this is not much different from other big clubs like Inter who sent 6 players and Juventus with 5 players just like Napoli.
This isn't really a big problem because this is indeed an advantage, especially with this, the rest breaks don't go more and more.