Can anyone confirm that this is a transaction from Coinbase to an external wallet, or is it an internal transaction? It wouldn't be the first time that panic was created around such transactions, only to find out later that the funds still remained with the same company, just at a different coin address.
In addition, Coinbase has announced that it keeps about 2 million BTC in its possession, so if it is correct or approximately correct, I ask the question, what does 5% mean in the bigger picture? Spreading panic should not be something serious members of this forum deal with - and this topic is nothing but exactly that.