I think that depends on each user personal experience,me despite not winning from a long time I have won before several times x2000-x3000 in Play n Go provider although nowadays this provider is offering casinos changeable RTP which I believe has made me not winning anything more than x400 in my best win from the latest session and latest free spins from Green Knight slot.
I think there are people who have hit it big in No Limit City which is notorious for their huge max wins that other providers lack most of the time but as you said it is extremely difficult to get such high multipliers without playing for a long time in such slots.
I tried Play N Go before, I got a x500 win from the lowest $0.26 base bet. At that time, I played the game Rise of Olympus. And I got x300 on the base bet, on the moon princess game. This is the biggest win I got from free spins in PNG. Unfortunately, after that win, until now I haven't tried to play it again. Because so far I've been too focused on playing on PGsoft, so I haven't experienced the high multiplier from PNG