Napoli's focus only has to be a champion regardless of defeat or not. I don't think it really matters too much, the most important thing is that Napoli win.
It's been too long since Napoli had to lose and last lost when they won 3 decades ago and at best they were only in position 2. Now is the right time for them to be able to bring back a trophy with a very big chance. Regardless of losing a few times or not later it doesn't matter, the important thing is they can continue to stay in the top position now.
What can be seen now is that Napoli are unbeaten in the 15 matches they have played this season and Napoli still have enough capital to become champions in Serie A this season if they have to lose several times. Because the number of points that Napoli has is very good for capital in the second half because they are also very aware that other teams will try more in the next match after the world cup so that Napoli will also continue to maintain their best performance during this season so as not to just drop after World Cup.
Napoli is 10 points ahead of second-placed Milan in the table. And it is very difficult for any team to close this 10-point gap. The performance of the teams after the World Cup break is likely to be somewhat erratic. However, I don't think Napoli will lose four games in a row. The Napoli team is not dependent on any particular player. So even if a player suffers an injury, Napoli will be able to maintain stability in their performance. And so I'd say it's going to be very difficult for any team to dislodge Napoli from the top of the table this season.