Napoli are a promising team in the Champions League as well. They only need to keep the same motivation after the return of this break. In that case they can have one of their most successful seasons in the Champions League as well. Frankfurt is an easy target for them of course. I don't expect any surprises.
But by the quarter finals, things are going to get really serious. They are most likely to have a draw against big title contenders. If they somehow get a lucky draw then they can reach semi finals easily. The luckiest one would be the winner of Milan - Tottenham or Club Brugge - Benfica matchups.
In this season Napoli is giving amazing performance in Serie A and Champions League with they won against Liverpool and having big gape in Serie A table against their opponents is surely giving them good advantage, and they will be able to play pressure free game after the break and in Champions League as well.
They will face Frankfurt which is surely an exciting side with good prospectus in Bundesliga and Champions League even Napoli is hot favourite but still things are not good for both teams because need extraordinary quality and performance for the win into this match and having spot into last eight if Napoli win then surely they could be able to have tag of favourite for the last four as well.