I believe that Ronaldos exit will help Manchester United when they face Barcelona, because theyll not be distracted by his antics on and off the pitch. Furthermore De Jong and Deepay will most likely stay at Barcelona at least till the summer transfer window, but beyond that Barcelona will have to convince them to stay otherwise Im sure that theyll move on to a club that makes them feel valuable.
Ronaldo himself has rarely been played by Ten Hag in the main squad. so Ronaldo's departure will not bother United. the match against Barcelona, of course, is a game of tactics. those who can overcome the opponent's tactics will get the victory.
there is still enough time, I'm sure both teams can focus first on their league. quite a long preparation, hopefully, the fight will be entertaining.