Both are in different performance. When talking about favorites, I prefer Barcelona to win the match. The match results achieved by Barcelona in the domestic league are in a good position. Even though this cannot ensure the final result, from the attack, Barcelona's goal productivity is superior than MU. Hopefully this can be a good provision for Barcelona and get full points.
Yes, maybe we will say that when we see Barcelona now. But on the other hand, Erik Ten Hag, with all his strategies, succeeded in bringing Manchester United more solidly in defense, and also they have started to be better productive in scoring goals. If Xavi Hernandez isn't smart enough to read Manchester United's gameplay then Barcelona might lose a place in the last 16. Once again I say that it is very difficult to predict who will win in this match.
Barcelona has a better h2h record against Manchester united even in some seasons when man united has had good performances in domestic leagues, So we shouldn't be concluding that Manchester United will win over Barcelona in this season's Europa league just because they are doing well in EPL. moreover, Barcelona isn't performing poorly in La Liga. I think when the time comes, it will only take the team with a lucky game plan to win the match. Let's not draw our conclusions based on their present performances.