I haven't really thought about it. I mean if the computer is connected to the internet, or it uses a problematic OS, then there will be a problem no matter what type of wallet you choose to use.
Well exactly --but I think it is far different from the hardware wallets, correct me if I am wrong but hardware wallets have a security feature that can protect themselves against malware infection or an OS that is already infected with malware.
I will hardware wallet over a paper wallet, but of course --it will vary always be in your hand how to protect it in a safe place.
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Yes this is the whole point of the hardware wallet! They will not be infected, especially if they are used with only an MicroSD Card. Still the paper wallet will get exposed, since it shows the private key in the PDF file it creates.