Well, I am way into 276k bets on Plinko with no 1000x win... so do not think you must hit it soon. Some people seem to think that you should regularly change seed, if you do not hit it within 40k bets, but I tried that.. before this and I just get the same result.
Gone are the days where you kind of had some guarantee that you will hit a 1000x within a maximum of 80k hits.

I have dug the hole so deep now... I just have to continue until I hit it... so that I can recover some of my losses.

What?? 276k bets without 1000x is robbery, even if you hit 5 1000x plinko b2b it shouldn't be enough to make it break-even. 80k nonce is nothing looks like, the main issue is to get max 130x series between 1000x series, otherwise, dead streaks will lead to huge expansion according to the game RTP if you know what I mean..
Yes, but also no

. It's about the odds in the sense that if you are in profit, that's all that matters. So, let's say you wagered 276k times, and each is 1 satoshi, so you wagered 276k satoshi, and you are in +1 satoshi profit, does that mean that you not hitting 1000x even once is bad? I do not think so.
Do no consider plinko the same thing as dice, because at dice if you wager on 1000x and wager 276k times, you will hit it for sure, without a doubt, would be near impossible not to hit it even once. But, if you wager on plinko, you could still win, it's not 100% or 0% situation there, which means that it could very well be a win without ever having a high return.