Unfortunately the people cooking up idiotic monstrosities like scrypt-jane and X11 have absolutely no clue what they're doing. Hey look I'll gang together ten ASIC-friendly algorithms and that just has to be ten times better, guys!
I can't speak for scrypt-jane, but X11 wasn't designed to be ASIC-proof. It was designed to delay the implementation of ASICs for coins (specifically Darkcoin). The dev said himself that he expects X11 ASICs eventually and they may even be beneficial once coin distribution has matured.