Go and check Manchester United States against Spanish sides they usually find it very difficult to play against Spanish sides to Cadiz and to Real Sociedad in th group stage they didn't get things easier as they think.
The improvement so far seems like Manchester United and Barcelona might result to many goals. Dembele Injured is a big blow, Xavi will miss him amongst the current players he played a pivotal role when Lewandoski was booked for three game ban
What you were saying was true. MU has very bad record against Barcelona. MU was so difficult to beat Barcelona. Xavi has raphinha as a replacement for dembele. Raphinha has proven itself during the match against real betis. I think that there should not be a problem with barcelone even playing without dembele. Barcelona is feeling so good with the composition of the current squad. I think that this gonna be a game that may not able to be won by united. It's still a match that can't be determined easily
One thing with Manchester United as you said is no matter the kind of form they are, they always appear little in the eyes of Spanish clubs. Starting from their big clubs to Sevilla. I dont understand how it happens and why it happens. But this time 10 may be ready to change the narrative especially since he will play the match and it is a home and away meeting.