It's not a problem that it's impossible to win or draw for a home team like Empoli, but with Napoli's current condition there is very little chance for Empoli to win or draw at home. Because Napoli are still very strong and often don't have any problems with their players at the moment, it has made it very difficult for the teams in Serie A this season to chase and fight Napoli in every match. So only the chances of winning and drawing are very small for the home team, not because it's impossible.
Napoli's match against Empoli is unlikely to end in a draw because, so far, Napoli has shown in every match that they can always win.
So when they meet Empoli in the upcoming match on February 26, it will be easy for Napoli to win. They are unlikely to give Empoli the chance to score.
At the moment the Napoli team's performance is on a positive trend after successfully beating FC Porto in the Champions League, so I believe that the Napoli players don't want to share the same points with the Empoli team at that meeting. Empoli is an easy opponent for Napoli because if you look at the last five matches in Serie A they have only won 1 win, in contrast to the Napoli team who have always won in their last five matches.
Even though Empoli are slightly superior because they are playing at home, they cannot stop the Napoli players who are very motivated to win the Scudetto title this season.