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I think it is not right to invest with loan. I think it would be better if we can invest our own money. After investing with loan, if the time of loan repayment is right, if our investment means a lot of loss, then we have a lot of pressure. So I think it would be better for us if we could invest our own money instead of taking loans.
Even Silicon Valley Bank's story shows us how bad is to take a loan. Even big banks have problems with returning all deposits even when they invest in rather reliable assets. If the situation in global economy goes wrong everything can happen, if bear market will last for years and years will you have enough to pay your debt while bitcoin assets will cost lower than you bought? It is a possible situation and that's why loans for investing is not a good idea, even for investing in reliable assets.