Games with outsiders mean nothing. In my opinion, bookmakers correctly assess the balance of power in this pair:
To Qualify
Feyenoord Rotterdam 2.00
AS Roma 1.75
It seems to me that Roma will win both matches (maybe draw once) and Feenord will have very little chance of scoring a goal. Now there are very few games left before the title, so the teams will play with increased motivation.
As long as they can keep up with Feyenoord's slick performance then it will be fine for Roma but of course at the moment Feyenoord have the upper hand. They topped the group stage and their big win in the last 16 against Shakhtar is definitely a confidence boost.
In terms of players and coaches, maybe in this case Roma is superior, but in terms of current performance, Feyenoord seems much better.