The match with Manchester City is a biggest one for Arsenal in rest of season as they are two direct competitors for the Premier League crown. Arteta and Arsenal don't have to win that match, they need to have a draw, prevent Manchester City to reduce 5 points gap and move on to collect points from other teams.
Don't think like that there are still 10 weeks to go, it's mean Manchester City can earn maximum of 30 points, it's enough to beat Arsenal at the top position. Arsenal always lost against Manchester City, so Arsenal still need to win regardless they're currently in a quite safe position and 8 points difference than Manchester City.
Maybe Arsenal have a slight advantage since Manchester City need to play at the other leagues, but it can put a pressure for Arsenal's players since Arteta will force them to win in this league, otherwise Arsenal will not get anything in this season.
Arsenal take an 8 points lead in the Premier League race into the international break, but for sure Manchester City will not let them rest easy as the campaign unfolds. Time and again this season, Arsenal have hit a crossroads and the same fear has surfaced, if they’ll bottle the league or win it. But one thing about this Arsenal side is that when they think they’ll drop their steam, they come through unbowed, if not unscathed. Now they’re all focused on the league title so they are going to eye the run-in with a healthier blend of caution and confidence. For Manchester city, the biggest issue facing them is the number of games that have to be wedged into the next eight weeks. 11 in the league, add an FA Cup semi-final against Sheffield United and a potential two-legged Champions League semi-final and it will be hectic. So I think fighting on three fronts could put City at a disadvantage against Arsenal, who only have eyes on the title.
The result from Manchester City's match against Arsenal on April 1st will be a very big one as it'll will decide wether Manchester City are going to battle for the top spot till last weekend if the premier league or they'll relatively be out of the race for who wins the title.
Arsenal knows how important that match will be to them and I expect them not to be nervous going into that match because they already has an 8 point gap over City.
Manchester City's main concern I think will be to win the Champions League this season which will be an added advantage to Arsenal who has been eliminated from Europa League.