I don't expect Real Madrid to run aground again in the Copa Del Rey. Even though Barcelona's performance is currently good, as much as possible El Real must exert all its abilities to be able to win a ticket to the final.
Of course it's not something good for Los Blancos to end the season without a title. Currently Madrid still has a chance in two more tournaments. But in my opinion, the most realistic trophy for Madrid is just the Copa Del Rey.
Though losing La Liga to Barcelona so Real Madrid don't want to lose Coppa del Rey to Barcelona too, it's not their priority which is Champions League indeed.
Players like Modric and Benzema know they don't have much time to win more Champions League and even their career is counting down. They won many Champions League (five) but winning one more as their biggest title before retirement which is coming, is good for them. That title will be a great farewell celebration for them in Real Madrid. Coppa de Rey does not have such important and attraction in those players.
Which three teams will be in the relegation zone is still completely uncertain. However, Elche does not see any chance of getting out of the relegation zone. They are the last team in the points table. Only 13 points in 26 games. And their performance is very poor. However, Valencia and Almeria have a chance to climb out of the relegation zone if they perform well and win a few matches. Valencia is only 3 points behind Getafe in 13th place in the table. If a team can win 2/3 matches in a row then I think they can move to a safe distance from the relegation zone.
Sevilla are trying to escape from this relegation zone but they will need to have some more good week days to enhance their position and make it safer. Valencia is another big name that has to join this survival competition. Look over Europe, it is a weird season when in Germany, Schalke 04 are struggling to survive and stay in Bundesliga.
I am not fan of either Sevilla or Valencia but I hope they will not be relegated after all.