One unique fact about the competition for Spanish representatives vs British representatives in Europe is that English teams have never been comfortable meeting Spanish teams. Even though they sometimes beat the Spanish team, they always get matched resistance.
In this case, no one should underestimate Sevilla because this team has a good record in the Europa League. Manchester United are aware of it and everything will be decided in 2x90 minutes because there are away and home matches. I hope Sevilla plays well so that this match will not be boring to look forward to.
I don't underestimate Sevilla, they were a strong club and has good records. But you can see how the condition of this club currently, they are very different from previous seasons. With the current squad and their performance during this season, I'm not sure that this team can give difficulty to Man United. I don't care about the statistic about Spanish representatives vs British representatives, it won't be applied in all seasons. For this season, I believe Man United will defeat Sevilla and qualify for the next round.
IMO, among the teams in the quarter-final, I think Man United is the favorite team to win Europa League title.