Napoli shouldn't have big problems about moving Milan out of their way in this round. There is a big difference between them already. Osimhen and Kvaratskhelia should be able to make difference as always. After that I would expect Napoli to have a matchup against Inter. And they can get past Inter as well and make it to the final round later on.
Whatever team they face in that round I'm feeling confident that it would be a really competitive game. Because Napoli are also very strong this season. They would do their best to make a big surprise.