Although he is financially one of the richest businessmen in the world, it is also worth noting that the share prices of his other companies could fall through losses on his Twitter purchase. In my opinion his main mistake was disregarding public sentiment. What is your concern?
I have no concern, new businesses don't just start making profit immediately they get launched. Although twitter isn't a new business but it's under a new administration so their new policy might crash the price but with time it'll recover and start making profits. Elon musk is a very successful entrepreneur and a business man.
Elon musk has made all the businesses he has been a part of very successful including the cryptocurrency market through his direct involvement with dogecoin so twitter will be profitable as his other businesses in due time.