Juventus - Sporting is going to be a quite close matchup in my opinion. I don't see a big difference especially after Sporting eliminated the biggest favourite of the tournament which was Arsenal in last round.
This is making Sporting a pretty dangerous team actually. Arsenal were one of the best attacking teams in the Europa League. But Sporting still somehow resisted them in Emirates also and made it to this round by penalties. Juventus are going to be a more different opponent for them though. Juventus would play more cautious against Sporting which can make things more interesting in this matchup. It feels like Juventus can get a good result in Turin in the first leg. In that case Sporting's job would be quite difficult home.
The Juventus of last season is not the Juventus of this season. There are many changes that have happened in the team. The club is playing extremely well present and they have chances of winning the Europa League. But on the other hand sporting Lisbon was able to eliminate one of the Favorites of the Europa League, which is Arsenal from the league. This has automatically made them one of the most favorites for the Europa League. So I wouldn't be surprised if any of them is eliminated by the other but I strongly tip the Sporting to be able to defeat the Juventus for the next round.