I am not sure as AC Milan are so experienced in Champions League and they also won against Napoli in Naples two weeks ago in Serie A. They only need a draw in Naples at the second match and will be able to join semi finals.
Napoli will bet all with Osimhen return to beat AC Milan. The striker can combine with Kravatskhelia to bring more pressure to AC Milan defense system. I don't know will Osimhem be completely ready for the match and will be able to play with his best.
AC Milan only leading one goal, Napoli still have a big chance to make at least a draw or beat AC Milan for scoring 2 goals higher than them.
I believe Osimhen will show an outstanding performance because this is a Champions league and they have beat AC Milan for many times in Serie A.
Both of this clubs are really prepare in this match as we can see their previous matches in Serie A, they were not let their key players to play or just play for 10-30 minutes to keep their stamina.