That is good news for Napoli if Osimhen will play in this second leg match and can appear at full strength, it is undeniable that his role for Napoli is very big. Napoli can play well with lots of chances but several matches without Osimhen present have made it difficult for them to convert the chances they create into goals.
Luckily enough Napoli was only 1 goal behind in the first leg, and they had to attack from the start so they could score at least 2-3 goals so they didn't need extra time or reach a penalty shootout because Napoli had failed in a penalty shootout with Cremonese in a domestic tournament because penalty shootouts will be very difficult to predict so it's pretty sure both teams will try to make the match end at normal time.
Napoli lost Kim Min Jae and Anguissa. Although Osimhen can play, the front line is strong but the midfield and back line are fragile. On the other hand, AC Milan is on fire. In the second leg Giroud will be the most dangerous. The problem is, there is no Kim Min Jae to look after him later. Even if Amir Rrahmani is there, it's not certain that he can fight 1 on 1 alone. Man Giroud's most dangerous target skill, Giroud was successfully locked by the Napoli players to aim at him so that the Milan winger and his midfield could move freely looking for scoring opportunities.
Besides that, in the second leg, I think Ac Milan will balance attack and defense. No longer relying on counterattacks. In my opinion, the match between AC Milan and Napoli will be fierce, and what is certain is that Napoli will not beat Ac Milan easily. My prediction is that the game will end in a draw.