The best moment to win is having such a small bet then you'll hit a high multiplier that makes you win huge amount, really amazing. Let's set aside how much he already lost because certainly he probably get those back (or somehow closer) after this win. Anyway, another player got lucky to hit a 12,864x multiplier with $0.1 bet on Blender Blitz slot.
It's true the best moment to win in slots is bet with small amount money and hit a high multiplier, but the question is when we will hit it? 
I did hit a high multiplier but it's not that high compared with those gamblers, I think I haven't hit any high multiplier since the last year until now due to lack of money to gamble continuously and my busyness.
But I believe those gamblers have spent more than the huge wins they got
However, if you lost more than 50 bucks until that point then what good would that do? This is why I believe that it is important to remember we can't do something like this for a long time. I hope that we do one day, I hope that we can make a big change, but the reality is that we won't hit that. House edge prevents you to keep doing that, eventually you will lose, even if it happens once or twice, mostly you will lose more than you earn.