Yes, we can trust reputable casinos but I still advice to be vigilant. Don't leave all your fundings as a bankroll on any gambling platform. Just deposit the amount you are able to lose, and withdraw winnings regularly.
That's what i'm doing. I only leave funds in my account to use for playing and when there's a winning amount, I immediately withdraw it to avoid losing it back. So far, I never had any problems in the casinos where I usually play. About the wagering requirements of the initial deposit, usually what I encounter is only 1x and it's easy to fulfill it for an average gambler like me who only use a small amount.
It is definitely not wise to gamble at such casinos if you already know about their rules and requirements since everyone understands that they are not really that lucky to be able to meet that requirement and still have something to withdraw at the end.
We always have a choice on where to gamble. If you already read their ToS and not agree with it then you can look for other casinos who don't have strict rules when it comes to wagering requirements and withdrawal. Aside from having fun, of course we also want to win too so if the casino's wagering requirement seems impossible to fulfill, it just shows they only want you to keep playing on their platform without a possibility to withdraw some earnings.