At this point, I actually trust Leverkusen to win this match against Köln. It is true that the opponent is not a very strong one. But at the same time, Leverkusen cannot afford to take things easy right now. The main target of Leverkusen right now is going to be finishing in the top 6 position. It will be hard for them to finish in 5th position.
I believe it will be better not to aim too high. Evening for the sixth position is going to be a very logical thing to do right now. Anyway, I believe they will be able to win this match today.
At the moment Bayer are losing 1-2 and the bookies see few chances for the game to turn around:
8.40 - 3.35 - 1.60
Even if Bayer is now focused on the game against Roma, this is a very unfortunate result for them, because despite the fact that Wolfsburg is playing Dortmund, there is still Mainz, which has a relatively easy game. Thus, Bayer risks losing their place, which ensures their participation in the Europa League.