I have some USDT and USDC in my portfolio that I'd want to stake in a "De-Fi" dApp without worrying about it in a long time. There are liquidity pools in Uniswap with attractive stake rates, but there's also Compound.Finance with its lending services. Both of these platforms are built on the ETH blockchain, so gas fees would be astronomically high. I've read about some platforms being compatible with Polygon (MATIC), but I'd have yet to see if it's worth the shot (especially in terms of security/reliability).
Do you know the safest way to stake stablecoins without breaking the bank? Also, do you think it's worth it? Or should I consider other options? Any suggestions and/or recommendations would be greatly appreciated. Thanks in advance.

This is just my opinion, isn't it better to stake a stablecoin on a centralized exchange? because some of the good ones here are Binance and Coinbase.
Because here, when you stake USDT, it gives 5% interest in a 6-months duration period of time, while in coinbase it is 4% for 3 months. Because if you want to do staking in Defi, as far as I know, the percentage of profit given is low whether it is usdt or usdc.
But you still have a choice if you want to stake your stablecoins, this is the link
https://koinly.io/blog/best-staking-platforms/