If you start with 1 satoshis, you can have some losses but I think the high rollers start at some higher numbers maybe even a few bitcoin in one bet lol.
I think there is still a lot of ignorance about the Martingale strategy; I have a buddy that I went to the casino with recently (in real life) and he kept talking about that with Martingale you couldn't loose and that is not possible to have 20-25 losses in a row.
I just noticed now that the maximum bet on Betfury is significantly limited. So, high rollers can not use one or more BTC per bet as the maximum size of the bet for regular users can't be more than 0.154 BTC, and for VIP users can't be more than 0.462 BTC. This means that if a regular user uses the martingale strategy, he will have the guaranteed loss after 23 losses in a row starting from the minimum bet of 1 sat, while a VIP user will have the guaranteed loss after 25 losses in a row.