Do you mean wars that involve weapons, people shooting each other? Yes, at some point a large-scale war will mean the end of humanity because weapons will be so advanced and destructive to the point it will blow up the entire earth. So, yeah even a madman would think twice to push the nuke button.

Anyway, I think the future wars would be in the case of information, economy, and tech wars. Whoever gets the upper hand will practically rule the world even if the border doesn't change.