It has been brought to my attention that you may hit some problems with scrypt coins when you run p2pool it just barfs something about scrypt missing.
Again the following is for Windows:
Go to https://github.com/develersrl/gccwinbinaries/releases
Click the green button 'gcc-mingw-4.3.3-setup.exe'
Run the installer.
Make sure to select the radio button 'Link with MSVCR90.DLL'
Open a new command prompt in the p2pool Directory
CD to the subfolder 'litecoin_scrypt'
Run the following: Make sure gcc is in PATH if this command doesn't work.
If it is and still errors with "gcc not found" Reboot system.

Thanks to:
http://www.reddit.com/user/xactfoxy