I'm really sorry to hear about your friend's tough situation. It's understandable that he's hesitant to take a job without proper benefits and stability, especially with his wife's health concerns. It's great that you're supporting him in his job search. One piece of advice I have is to explore alternative options like freelancing or remote work, which might offer more flexibility and potential for higher pay. Encourage him to network, update his resume, and consider any transferable skills he may have. Remind him to stay positive and persistent.
It's indeed hard to find a high paying job unless you have a great skills or background that would worth a high value of salary. But if you're really desperate, maybe it's fine to accept those job offers he have since he needed the money immediately for his family. He also need to find another source of income or a part time if possible. It could be exhausting but you need to make sacrifices.
Remote works are also effective since it gives you flexibility. Because if you really need to save up money for a short period of time, you also need to manage your time so it won't be wasted.