Nonito was most taller, So he get more range as compared to other people.The shorter boxer will be easy for the Nonito, he can crush the short boxer using his hand power.In addition he had a power punch compared to the Santiago.Santiago had win many old experience boxer using his power arm.This fight will against the two power arm fighter.So the game winner will be the maximum punch player.The Nonito should win the game against the Santiago to prove his power against the most powerful player.This will make them to prove his power and make other to think about the match, even this help the Nonito to get the championship.
Nonito Donaire could win this fight easily because of his natural speed and power but the problem here is if he can still manage to take punches and managed to survive up to 12 rounds of non-stop action. Because as we know, he is no longer feeling like his old self, and taking multiple power punches is way more harder than before. Most likely he will higher his chance to win when Santiago distances himself and will not gonna choose to throw multiple power punches throughout the rounds because he is scared of the counter punches from Donaire.
And that's why Nonito should take out Santiago early if he can. And if you look at some of his victories, usually it didn't last a full 12 rounds. So for me this might also be the case here, Nonito feeling Santiago early and if he can open up with his counter left then he might go and look for the early knockout.
For sure he has prepared a full twelve round fight, but it's better if he can win early because his money might not take a gruelling and long fight and just a momentarily slip in the concentration might give Santiago to go for a knockout as well. So the risk is there as the fight goes longer for him and for Santiago he might want to prolong the fight and test Nonito's stamina.