It all depends on the nature of the business and your knowledge over the business.
For any CEO to sell off a business there has to be an issue over the business. If you're or were a staff of that business I think that would give you an edge and a plus to actually know what you're buying and how to manage the business.
Starting a new business would also require an expert in that field that's if it's a company. It would require you getting or hiring capable hands to start up a new business.
My own take is to start up a new business and be in charge from scratch .