It's really very simple and it applies in Bitcoin, and maybe to a very small set of those other coins that have an incentive structure that makes sense, but mainly Bitcoin.
Yes, In the long run BTC is here to stay and these are my thoughts about BTC but on the way i am also learning BTC also make people poor but only those become poor who enter without some aim and knowledge because at least a person with determined purpose of getting profits or saving money for longer period of time against inflation cannot ever become poor. The meme is just for fun here and i have some more in my phone here is another one to explain the situation: (i know its not meme)

This post enough for me to understand the potential BTC had but i did not had the opportunity to get that much BTC because i just entered market few months ago. But the person in the tweet made some next level mistake and i also watched another video which was uploaded on YT back in time where the representative of the video was begging people to buy BTC at least of $1 only.
In his situation, he's the MEME.
But to be honest, if I had Bitcoin during 2011, I don't believe that I would have the same conviction in HODLing Bitcoin as I have now. The biggest exchange was a website domain registered for Magic The Gathering cards, no one accepted it or was interested in it outside of the community, and was the Silk Road already online? The Silk Road might be the only service that might make smarter HODLers say, "This is going somewhere". But I'm the stupid one.