If you mean multiple wallets in the same HW, I fail to see how that's going to be useful since not only will it have the same effect of generating more addresses inside a single wallet, but there will also be more mnemonics to write down.
There's the beauty of it! You don't need to write down any mnemonics! For the low price of only $10 per month per mnemonic, Ledger will store them all for you! Such secure! Many value! Wow! 
There is an argument to be made to have a second hardware device which you can use for the emergency recovery of your funds should your primary device be lost, stolen, or damaged, so you don't need to risk importing your seed phrase in to a hot wallet. But if you can always just buy a new device should this happen and you are willing to wait a few days. And if you do need an emergency back up device on hand, then you can pick up something cheap like a SeedSigner and not splash out $300 for this NFT picture frame.