The reason why players get injured more often than not is because of the schedule, there are too many games and the players obviously feel this fatigue and it can get them injured. We've seen managers like Pep Guardiola and others complain about the schedule, it is even worse for big clubs like City and Real Madrid that have to compete in 3-4 competitions, and have the quality to go all the way, which inevitably means more games.
Well it is what it is anyway, and the players have to play, if there are injuries in the team, it gives a chance to those who are frequently on the bench, they can take the opportunity to prove themselves and fight for a starting place in the team.
Manchester united Central back made complains concerning the schedule and lots of competition including the extended extra minutes that's added to games and how it's affecting players and causing fatigue as well, I you look at Manchester United you'll see that they've been suffering due to lack of quality options in their Substitution list and I've observed that clubs that only have quality players in their first 11 that suffers the most especially when they've got numerous competitions to compete.
Thank goodness that the fans and players kicked against the Super league which many big teams wanted introducing if not it would has been worst on this players and he'll see a lot being sidelined due to Fatigue and it would make the game very boring to watch.