Nothing is impossible in football, because in football anything can happen, even though the two clubs that will meet display very different statistics.
I think it's clear that Barcelona will dominate the game, because that's what they're used to.
I also hope the same, hope Sevilla can play well, yes at least they can break every attack that Barcelona will launch. Winning is a very difficult thing for them to get, so a draw is a good result for them to get in this match. Their target does not need to be too big, although victory is the best thing.
I think a draw from Barcelona is worth a win. Sevilla has been getting very bad results in the last matches and the average age is also quite high. When these factors come together, I do not expect them to have a fully productive season. Of course, they may get bad results this season, but they may also get surprising results. I think there is a small chance they can surprise the Barça match, but the more likely part is of course a Barça win.
Barcelona having some trouble in last game against Mallorca, and they lost two points which are surely going to hurt them, but now they are playing at home against Sevilla which is also fighting back after having the worst result in three early games but now this time I have feeling things are going to be easy for the Barcelona, and they will win easily without any problem.
Sevilla never won against them in La Liga on road which is big disadvantage for them and their quality is also not near them with recently they improved but still need more improvement for having better things for the rest of this season but in case of other than win Barcelona can face serious dilemma because having drop of points can hurt them badly for the title race.