what I see at the moment is that the opponent that will make it difficult for Arsenal to qualify for the next round is Lens or Sevilla who are unbeaten in this UCL match while Arsenal experienced 1 defeat against Lens at that time and I can not imagine whether Arsenal will be able to beat Sevilla in the match which will come but what is certain is that the opportunity for draw seems very certain but playing away will not make it easy for Arsenal to defend attacks from Sevilla and it looks like Arteta will think of many ways to anticipate strong attacks from Sevilla with defensive formation.
Sevilla is the home team, and it will be very difficult for Arsenal to play this match away. But before this match, Sevilla will have a very difficult match in La Liga with Real Madrid, so Arsenal can count on the fact that Sevilla can spend a lot of effort in this match, although perhaps for Sevilla in this case the Champions League match will be a priority. Before the match with Sevilla, Arsenal will face Chelsea, perhaps not the most difficult opponent, but in recent matches they have begun to play better.
Playing a defensive formation is something I don't think arteta will be doing, if against Manchester city their biggest rivals they didn't play a defensive pattern I don't think they would do that with Sevilla, I don't think Sevilla have such an attacking/strike force that will be enough to send arsenal defensive arteta will be having Saka right in the front to get se creativity for chance's and get Gabriel to score the goals.
Sevilla is actually going to have it really hard contrary to the idea of Playing from home been and advantage for them, I feel it's not an advantage enough. This match as got so much at stake for arteta as it will be one of the determinants of how far he will go in the UCL so I'm sure he will leave nothing to making sure he secure a win or a draw at worse.
Just before the UCL Sevilla have got a domestic league game to play which will definitely affect their productivity at the UCL because the game is aswell important to them so they are going to invest some more effort in that game, this could be an advantage for arsenal, in la Liga is not considered a strong team so I doubt if that strength will be seen in the UCL except they will be lucky but then I'm most certain of a win for Arsenal or a draw.