Playing at home will not guarantee that Sevilla can beat Real Madrid and maybe Sevilla must be prepared to accept the fact that Real Madrid has been impressive so far. In terms of squad depth, it is clear that there is a huge difference and Real Madrid seems to have no gaps that could allow them to lose.
I also have that view for Real Madrid if the opponent is Sevilla, because everyone has seen how these two teams have performed in the several matches they have played this season. So it is quite clear that Real Madrid has the possibility of getting full points at home to Sevilla in this week's match, besides that the match with Sevilla is an opportunity for Real Madrid to gain points distance from rivals such as Girona and Barcelona.
Maybe Sevilla can beat Real Madrid if they succeed in pressing and continuously attacking. But attacking continuously is not a good option and Real Madrid with its counter attack could destroy Sevilla within 90 minutes. The safe bet is of course on Real Madrid and I would bet on Real Madrid without the slightest doubt.
Maybe many people will not hesitate to bet on Real Madrid because in general Sevilla is not a fairly equal opponent to Real Madrid so Sevilla may have to accept the bitter reality of being defeated by Real Madrid at home. And I am very sure that Real Madrid will make it difficult for Sevilla first by continuing to build attacks from the start so that no goals are conceded into the net.