The negative affect from international break is when some players are return to their clubs with got injured so that's why some of European managers doesn't really like if their players playing with their national team and recently it just happend to Tottenham that confirmed their defender player Cristian Romero condition was not certain after defend Argentina national team and if Romero will not available this weekend i think this is big lost for Tottenham because so far his duet with Micky van de Ven was very strong to guarded Tottenham defensive lines and for every matches Romero always be performing well so if Romero not available when Tottenham playing against Fulham next weekend i think this will have any affect for Tottenham performance later
there no other way to reject players who will compete for their country, but you dont need to worry about this and we also can not blame anyone because this is responsibility football players who must professionally defend national football matches and if indeed currently Spurs are still is known as strong team at the moment, Ange Postecoglou should be able to condition all of this even though there are players who are injure, but if the coach is really influential in improving Spurs this season, he can rotate wisely and the match against Fulham might be a little different in Spurs performance, but its impossible can lose to Fulham because Spurs still have big advantage playing at home.