Arsenal have already lost this season (to Lens in the Champions League) so this is not the first defeat. But that doesn't really matter, the important thing is that if you take the percentage of points they get now - 72% is pretty good and even often enough to win the title in many leagues, but it is definitely lower than the percentage that is needed when your opponent is City. Now all hopes must be directed towards Tottenham and hope that they will create the greatest meme (title after Kane's departure)

If he meant the first in EPL and this is the first lost of arsenal. Glad to see that anthony gordon has become a nightmare for arsenal in this match. Totenham is the only team that is holding a record being unbeaten till this time. It will be facing chelsea.
It will be so good to see chelsea will able to play better than the previous match to beat totenham. Son and maddison are the only threats from totenham. My feeling said if manchester city will be winning the trophy again this season.
City is now having three points gap toward arsenal at this moment. It's a very good result for the newcastle to beat gordon. That proves that if newcastle is also very strong at this moment.
Arsenal potentially become trophyless club again this season. I have no doubt about that.
He wrote "this season" so there's no point in guessing what he meant. Newcastle is really strong, as are Arsenal, and also Liverpool + Tottenham. The problem is that they take points from each other, which works in City's favor.
As for titles, maybe Arsenal will win the Champions League this year, that possibility exists, plus it would be a really “fresh” event. After all, even City, which won the Champions League for the first time last year, is already completely boring to everyone.
That would be refreshing if Arsenal does at least reach the final. Whether they win it, that remains to be seen but having them in the final would be nice. I still think that having Manchester City in the final would be also nice because they would still have to prove they can defend it. I usually prefer final participants to be from different countries, but if it was Arsenal vs Manchester City, that would definitely be worth watching for many reasons.