But indeed at this time with a score of 2-0 it was also very enough to bring them to the most comfortable position at the top of the standings with a difference of 2 points from Juventus as the closest competitor.
Two points difference is not a comfortable lead to pass your closest opponent with. To me, the league is still at its early stage and anything can still happen at anytime. Inter Milan are in a very tight position even though they are the one leading in the top table now. They need to show consistency in their games and continue the winning run for a long time to come to have a comfortable lead over Juventus, it will be safer for them that way than gambling and giving their points away easily.
Inter Milan must be aware about the potential drop in their performance. They need to keep their motivation in competing the title. The bigger challenges will happen in the second half, sometimes many teams drop their performance when it is toward the second half. You're right that one of the solution is about rotating the players on the starting lineup. Inzaghi needs to try this way, it also minimizes the chance of injuries among the players, too.
This is one of the issues that most of the managers don’t look into when they are enjoying the game of a particular set of players or if they are always winning consistently. Fatigue is there and it can come at anytime when they don’t expect it, it could be during an important match that those players are most needed. Rotating of players is the best for all team most importantly, when you don’t have enough quality squad depth in your team.