problem now is that Wolfsburg will act as hosts, while Wolfsburg already knows Leipzig weaknesses and even though Leipzig in terms of player performance is superior in depth, if Wolfsburg already knows Leipzig weak points, it will be a little difficult to win unless the Leipzig coach has to close every gap in their weaknesses by this team and I would indeed expect Leipzig to win but looking at the current performance of both teams I have several betting options and the main thing is that it is better to bet on a total score under 3.
Personally I still think Leipzig still have the better chances of winning in this match than Wolfsburg does, it's usually an advantage to be at home in any match because you have the biggest fans base and your morales will most likely be high but Leipzig has been better in performance and have the dept than Wolfsburg as rightly stated.
I sure the coach of Leipzig will be aware that his weakness is known by his opponent so he will definitely make sure to cover up for it so it wouldn't be used against him, so Wolfsburg shouldn't expect it was because they have the home advantage and at same time know the teams weakness, it's very possible they would work on that weakness just before the match because they know how much three points will do for them.