With 4 defeats and 1 draw owned by Wolfsburg actually i don't feel this will be a heavy burden for Leipzig because after all the comparison of performances is much different now even though Leipzig is playing away in this match but indeed some player are still not available and losing Dani Olmo in the squad is still one of the scourges for Leipzig.
Im still pretty sure the difference of more than 2 goals in this match will still happen because I don't think this will be a big problem for Leipzig to face a painful club like Wolfsburg.
Leipzig are favorites against Wolfsburg. But the match is Wolfsburg's home match. And while Wolfsburg's performance in away matches has been poor this season, the team has been performing well in home matches. That's why the Leipzig team must play well if they want to earn full points from this match. Wolfsburg's defence is quite weak. If Leipzig's players can take advantage of Wolfsburg's weak defense, Leipzig will surely win. But even then, Leipzig's players will have to perform carefully. Wolfsburg players have the ability to surprise everyone by defeating a team like Leipzig at home.
As I said before I don't think it will be a problem regardless of it being a home match because Wolfsburg's current performance is still not perfect and even 4 defeats from the last 5 matches they did it is proof that they are still quite weak at the moment.
Indeed playing home will provide more advantages especially with greater support from militant supporters but in the end the difference in strength will also definitely have an effect.
Currently Leipzig still intends to keep forcing sticking VFB which is only 1 point away so they will definitely strive for 3 points against Wolfsburg at any cost.