I also see Leipzig winning this match but not with wide margin since I've taken time to analyze their last 5 games with each other and there's not been that much goal differences in their matches. The last time both clubs met, Wolfburg won at home with a goal ahead of Liepzig. But the match they played before that last match, it was Liepzig that won over Wolfburg with 3 goals to none. And that was a Bundesliga R21 challenge unlike the earlier which was DFB Pokal.
Taking decisions from those last challenges they had coupled with the performance of Liepzig lately which has been good enough to count on, it is pretty much easier to agree that Leipzig will win this match. Leipzig is currently standing in the position of 4 on the Bundesliga table with two points well over Dortmund. If they win in the next match which is on the 25th of this month, they have more chances to to move ahead of other clubs in the table.
Leipzig is one strong team in the German Bundesliga and they stand a lot of chances when they face other teams. Though in recent games, they've been victorious but they've gone less in the goal margins, they're most likely to be the victor in every game they have but they have to work on making the goal margin tangible and concrete.
Their position in the league is threatened because of they're not able to meet up, Dortmund who's 2points below them may end up scoring more goals then overshadowing them and pushing them below the table.
They should be able to secure a win with a wide goal margin. Although their next game is seeming promising and it's more likely that they'd secure the 3points in the game, they have the quality of players and managerial board they'd need so most definitely it's just a few effort extra they'd be needing to add.