It is very likely that Chelsea will secure full points in the match against Newcastle, even though Pochettino squad will act as the visiting team. I think it's very reasonable, because the Blues have experienced an improvement in performance by successfully beating Tottenham and forcing Man City to share points in the previous match. Actually, Eddie Howe's squad also has a chance to make a surprise, but currently many Newcastle players are injured.
Eddie Howe is missing 13 players, some of whom are injured and some of whom are suspended, so I think it's very reasonable that Chesela will take advantage of their weaknesses to secure full points. You could say Newcastle was just lucky because they played in front of their own supporters, otherwise their situation was very complicated.
Even though in the previous 2 matches they did very well but facing Newcastle I don't think it will be easy because I still feel that it depends on Newcastle also providing resistance to Chelsea because usually with a fast tempo and high tension, Chelsea is always able to progress rapidly in 90 minutes of the match even there will be some surprises if the tempo is like this but when the tempo slows down and Newcastle can manage the rhythm well obviously this can be troublesome for Chelsea.
At the moment they (Chelsea) will be the favourites with quite good results in the previous 2 matches and with Newcastle's situation limping because some players, especially the striker, are injured, it is difficult for Newcastle to dismantle Chelsea's defence but I still feel that this match will be a draw.