But also remember it is just a very small piece of hardware we handle. And they are not the most rugged build. These buttons last more in theory if you press them more carefully. If you push the hell out of them every time you need to click you will get them damaged very soon.
In general it is designed to be independent and resistant to online threats, but if the intensity of our use is too frequent, as you say, there could be loopholes that can be entered. Yes, there is no single system that is safest when used and related to activities in this digital world. If it is safe, then we never hear of bad incidents in the crypto market related to online threats.