Understanding is the main thing that must be paid attention to before they decide something, as you said that we must be ready to accept defeat and that doesn't mean we are ready to just win, I would say you are a coward and irresponsible if you only want to win but don't want to lose. Controlling expectations and limiting them will be very useful to stay safe..
Of course those who think only winning in gambling they normally lose the most. There are some gamblers who do so much research that seems they will not loss. But when the results of their bets show up their reports convey great loss. I think there are times when you have to accept where you're sitting on the losing side but if you're lucky you can get big rewards. After getting a win in gambling one must prepare to lose. If luck is good there may be a chance to win a second time. Every time you win, your chances of winning will decrease and you will have to accept the loss. A gambler can never ignore loss.