Real Madrid have more solid with defensive by conceded 9 goals and success scored 33 goals of 15 matches, with home match seems Real Madrid more favorable team than Real Betis on matchday 16.
Playing away and of course by playing several key players I think is enough for Madrid to win and get the full three points against Betis tomorrow, I'm not sure Madrid will share the points let alone lose the full points considering that Girona will always be ready to replace their position at the top of the Laliga standings if madrid dropped points in tomorrow's match.
Betis will of course also play as hard as possible in front of all their fans, of course it will make it difficult for Madrid to get full points, I think Madrid will get full points even though they have to play away from home if you look at Madrid's strength which is currently on fire. My prediction is that Madrid will win 0 - 2 in the second match tomorrow