Crypsty is backed by a "real company" and it is highly unlikely they will ran away with tons of customer money.
btc-e is super-fast (most of the time the site is fast and easy to use) with good volume, and many opportunities to make short-term trades.

Putting ~60 to 70% into Crypsty and 30 to 40% into btc-e is a reasonably safe plan* and gives you plenty of chances to make money.
*For maximum safety, make 100% profit ASAP and get your original investment off the exchanges.